| 产品详情 |
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| Antigenic Specificity | ADAM17 |
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| Clone | BA0391 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | mouse, human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, IF, IHC-P, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-ADAM17 Recombinant Antibody (BA0391). This product is a mouse antibody that recognizes ADAM17. The antibody BA0391 can be used for immunoassay techniques such as: FC, IF, IHC-P, WB. Black et al. (1997) cloned a human cDNA encoding ADAM17, which they called TACE. The gene encodes an 824-amino acid polypeptide containing the features of the ADAM family: a secretory signal sequence, a disintegrin domain, and a metalloprotease domain. Expression studies showed that the encoded protein cleaves precursor tumor necrosis factor-alpha (TNFA; 191160) to its mature form. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound p |
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| Immunogen | Human ADAM17 amino acids 215-315 |
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| Other Names | ADAM Metallopeptidase Domain 17; Tumor Necrosis Factor, Alpha, Converting Enzyme; Snake Venom-Like Protease; TNF-Alpha Convertase; EC 3.4.24.86; TACE; CSVP; ADAM Metallopeptidase Domain 18; TNF-Alpha Converting Enzyme; TNF-Alpha-Converting Enzyme; CD156b Antigen; ADAM 17; ADAM18; CD156B; NISBD1; NISBD |
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| Gene, Accession # | Gene ID: 6868, UniProt: P78536 |
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| Catalog # | CBMAB-0025CQ |
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| Price | |
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| Order / More Info | ADAM17 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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