| 产品详情 |
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| Antigenic Specificity | Sprouty Homolog 4 (Drosophila) (SPRY4) (aa 306-322) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),ELISA,Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS. SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.Synonyms: Sprouty-4, SPRY4 |
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| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 306-322 of Human Sprouty-4 protein. |
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| Other Names | SPRY4|LOC100218545|HH17|A030006O18Rik|sprouty4 |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN129626 |
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| Price | |
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| Order / More Info | Sprouty Homolog 4 (Drosophila) (SPRY4) (aa 306-322) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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