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Product Name | (R)-Bromoenol lactone |
Description | The PLAs are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components.{6940} The iPLA2 are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-BEL is an irreversible, chiral, mechanism-based inhibitor of iPLA2γ. Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 µM.{12978} (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM. |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | (R)-BEL |
Gene, Accession, CAS # | CAS: 478288-90-3 |
Catalog # | 10006800-500 |
Price | |
Order / More Info | (R)-Bromoenol lactone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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