| 产品详情 |
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| Product Name | (R)-Bromoenol lactone |
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| Description | Purity >98%. The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2 ) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase Gamma (iPLA2 Gamma). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2 Beta except at high doses of 20-30 µM. (R)-BEL inhibits human recombinant iPLA2 Gamma with an IC50 of approximately 0.6 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl)-2H-pyran-2-one, (R)-BEL |
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| Gene, Accession, CAS # | CAS: 478288-90-3 |
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| Catalog # | LS-H5635 |
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| Order / More Info | (R)-Bromoenol lactone from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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