| 产品详情 |
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| Antigenic Specificity | OPN-R |
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| Clone | 24 HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | OPN-R Antibody (24 HCLC), ABfinity™ Rabbit Oligoclonal. Osteopontin is a 34kDa extracellular matrix protein with a cell binding domain. It was originally identified as a major component of the non-collagenous organic bone matrix, however, it has subsequently been demonstrated in a wide range of normal adult tissue and body fluids. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors |
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| Immunogen | n/a |
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| Other Names | Osteopontin, Bone sialoprotein 1, Secreted phosphoprotein 1, SPP-1, Urinary stone protein, Nephropontin, Uropontin, OPN, BNSP, SPP1, Thrombin-cleaved OPN, Thrombin OPN-R |
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| Gene, Accession # | Entrez: 20750, 25353, 6696; Uniprot: P08721, P10451, P10923 |
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| Catalog # | 711215 |
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| Price | |
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| Order / More Info | OPN-R Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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