| 产品详情 |
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| Product Name | MLS-573151 |
| Description | MW: 377.5. Purity >99% (TLC); NMR (Conforms). Cdc-42 inhibitorActivates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor1. Promotes skeletal muscle autophagy via activation of FoxO3a2. Controls smooth muscle cell hyperproliferation in vascular disease3. Cell permeable.Scientific Background: MLS-573151 is a potent and specific inhibitor of Cdc42 a small GTPase of the Rho-subfamily (IC50 |
| Size | 5 mg, 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [AICAR; 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside; Acadesine; 4-[3,5-diphenyl-4,5-dihydropyrazol-1-yl] benzenesulfonamide] |
| Gene, Accession, CAS # | CAS: 2627-69-2 |
| Catalog # | MBS515010 |
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| Order / More Info | MLS-573151 from MYBIOSOURCE INC. |
| Product Specific References | 1. I Chopra et al. Diabetologia 2012 55:783 2. AM Sanchez et al. J. Cell Biochem. 2012 113:695 3. N Ferri et al. Vascul. Pharmacol. 2012 56:9 |
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