产品详情 |
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Antigenic Specificity | Spectrin beta-3 |
Clone | 11HCLC |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Spectrin beta-3 Antibody (11HCLC), ABfinity™ Rabbit Oligoclonal. Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordin |
Immunogen | n/a |
Other Names | Spectrin beta chain, non-erythrocytic 2; SPTBN2; KIAA0302; SCA5 |
Gene, Accession # | Entrez: 20743, 6712; Uniprot: O15020 |
Catalog # | 711584 |
Price | |
Order / More Info | Spectrin beta-3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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