| 产品详情 |
| Edit |   |
| Antigenic Specificity | Spectrin beta-3 |
| Clone | 11HCLC |
| Host Species | Recombinant Rabbit |
| Reactive Species | human, mouse |
| Isotype | IgG |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot: 1-2 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Spectrin beta-3 Antibody (11HCLC), ABfinity™ Rabbit Oligoclonal. Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordin |
| Immunogen | n/a |
| Other Names | Spectrin beta chain, non-erythrocytic 2; SPTBN2; KIAA0302; SCA5 |
| Gene, Accession # | Entrez: 20743, 6712; Uniprot: O15020 |
| Catalog # | 711584 |
| Price | |
| Order / More Info | Spectrin beta-3 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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