| 产品详情 |
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| Antigenic Specificity | mGluR5 |
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| Clone | 464818 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mGluR5 Monoclonal Antibody (464818). GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness. |
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| Immunogen | n/a |
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| Other Names | GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5 |
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| Gene, Accession # | Entrez: 2915; Uniprot: P41594 |
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| Catalog # | MA5-24185 |
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| Price | |
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| Order / More Info | mGluR5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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