| 产品详情 |
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| Antigenic Specificity | mGluR5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 5.6 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mGluR5 Polyclonal Antibody. GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness. |
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| Immunogen | n/a |
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| Other Names | GPRC1E, MGLUR5, mGlu5, metabotropic glutamate receptor 5, metabotropic glutamate receptor 5 variant F, metabotropic glutamate receptor 5 variant G, metabotropic glutamate receptor 5 variant H |
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| Gene, Accession # | Entrez: 2915; Uniprot: P41594 |
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| Catalog # | PA5-32861 |
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| Price | |
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| Order / More Info | mGluR5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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