| 产品详情 |
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| Antigenic Specificity | mGluR5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mGluR5 Polyclonal Antibody. GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness. |
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| Immunogen | n/a |
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| Other Names | Metabotropic glutamate receptor 5 [Precursor]; mGluR5; GRM5; GPRC1E; MGLUR5 |
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| Gene, Accession # | Entrez: 108071, 2915; Uniprot: P41594, Q3UVX5 |
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| Catalog # | PA5-13361 |
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| Price | |
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| Order / More Info | mGluR5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25131692 |
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| 产品资料 |
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