| 产品详情 |
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| Antigenic Specificity | mGluR5 |
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| Clone | S75-3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2A |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (PFA fixed): 1:200, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mGluR5 Monoclonal Antibody (S75-3). GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness. |
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| Immunogen | n/a |
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| Other Names | mGluR, metabotropic glutamate receptor 5, metabotropic glutamate receptor 1, mGlu5, mGlu1, mGluR5, mGluR1, GPRC1E, GRM5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5 |
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| Gene, Accession # | Entrez: 108071, 24418, 2915; Uniprot: P31424, P41594, Q3UVX5 |
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| Catalog # | MA5-27691 |
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| Price | |
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| Order / More Info | mGluR5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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