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| Product Name | Hepatitis C Virus Nonstructural protein 3 Recombinant |
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| Description | Purity >95%, as determined by SDS-PAGE. The NS3 protein of hepatitis C virus (HCV) is a bifunctional protein containing a serine protease in the N-terminal one-third, which is stimulated upon binding of the NS4A cofactor, and an RNA helicase in the C-terminal. The C-terminal 450 amino acids of the NS3 protein manifest a polynucleotide- stimulated NTPase activity, a 3-to-5 unwinding activity, and a single-stranded polynucleotide binding activity. |
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| Size | 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | HCV NS3 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems. |
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| Other Names | [hcv; hepatitis; nonstructural; ns3] |
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| Gene, Accession, CAS # | HCV NS3, Accession: AAY84772 |
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| Catalog # | MBS553077 |
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| Order / More Info | Hepatitis C Virus Nonstructural protein 3 Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • relative replication capacity and selective advantage profiles of protease inhibitor-resistant hepatitis c virus (hcv) ns3 protease mutants in the hcv genotype 1b replicon system .Antimicrob. Agents Chemother., Mar 2008; 52: 1101 - 1110. • a hepatitis c virus (hcv) ns3/4a protease-dependent strategy for the identification and purification of hcv-infected cells .J. Gen. Virol., Dec 2006; 87: 3587 - 3598. • vx-950, a novel hepatitis c virus (hcv) ns3-4a protease inhibitor, exhibit |
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