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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 1A |
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| Description | 31-210aa; Partial. MW: 47.6kD. Purity >90% as determined by SDS-PAGE. Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-vira |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60] |
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| Gene, Accession, CAS # | TNFRSF1A, Gene ID: 7132, Accession: NP_001056.1 |
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| Catalog # | MBS717308 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 1A from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor.Loetscher H., Pan Y.-C.E., Lahm H.-W., Gentz R., Brockhaus M., Tabuchi H., Lesslauer W.Cell 61:351-359(1990) Molecular cloning and expression of a receptor for human tumor necrosis factor.Schall T.J., Lewis M., Koller K.J., Lee A., Rice G.C., Wong G.H.W., Getanaga T., Granger G.A., Lentz R., Raab H., Kohr W.J., Goeddel D.V.Cell 61:361-370(1990) Molecular cloning and expression of human and rat tumor necrosis facto |
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