| 产品详情 |
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| Antigenic Specificity | PRDX1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PRDX1 Polyclonal Antibody. Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at their active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Prx I to IV have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Prx I. The active site cysteine (Cys51) is oxidized to cysteine sulfenic acid (Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow proces |
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| Immunogen | n/a |
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| Other Names | MSP23, natural killer-enhancing factor A, NKEFA, PAG, PAGA, PAGB |
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| Gene, Accession # | Entrez: 18477, 5052; Uniprot: P35700, Q06830 |
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| Catalog # | LF-PA0004 |
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| Price | |
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| Order / More Info | PRDX1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 17145963, 17855346, 19721077, 20488244, 26117319, 27546460 |
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