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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 10B protein (TNFRSF10B) (Active) |
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| Description | 52-183aa, Partial. MW: 14.8 kDa. Purity ≥97% as determined by SDS-PAGE and HPLC. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. {ECO: |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD antigen CD262] |
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| Gene, Accession, CAS # | TNFRSF10B, Gene ID: 8795, Accession: NP_003833.4 |
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| Catalog # | MBS969347 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 10B protein (TNFRSF10B) (Active) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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