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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein (TNFRSF11B) (Active) |
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| Description | 22-194aa, Partial. MW: 19.7 kDa. Purity ≥95% as determined by SDS-PAGE and HPLC. Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL b |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Osteoclastogenesis inhibitory factor] |
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| Gene, Accession, CAS # | TNFRSF11B, Gene ID: 4982, Accession: NP_002537.3 |
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| Catalog # | MBS969418 |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein (TNFRSF11B) (Active) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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