产品详情 |
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Antigenic Specificity | GPR77 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 50 ug |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 25-33 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPR77 Polyclonal Antibody. C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis. |
Immunogen | n/a |
Other Names | GPR77, G-protein coupled receptor 77, GPF77, C5L2, G protein-coupled receptor 77 |
Gene, Accession # | Entrez: 27202; Uniprot: Q9P296 |
Catalog # | PA5-33374 |
Price | |
Order / More Info | GPR77 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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