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Antigenic Specificity | PPIG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PPIG Polyclonal Antibody. PPIG belongs to a highly conserved class of cyclophilins that function as peptidyl-prolyl-isomerases (PPIases) to catalyze the conversion of cis-proline to trans-proline in a polypeptide chain. PPIG contains an amino-terminal cyclophilin domain followed by Nopp140 repeats that are involved in its function as a nuclear chaperone. The carboxy-terminal of PPIG contains a SR (arginine-serine dipeptide repeat) domain that is involved in pre-mRNA splicing and processing. PPIG interacts with the carboxy-terminal domain of RNA polymerase II as well as several other SR family splicing factors. These interactions lead to changes in localization and conformation and suggest a regulatory role in transcription and pre-mRNA spli |
Immunogen | n/a |
Other Names | CARS-cyclophilin; CASP10; Clk-associating RS-cyclophilin; OTTHUMP00000204761; OTTHUMP00000204762; PPIase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10; cyclophilin G; peptidyl-prolyl cis-trans isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); rotamase G |
Gene, Accession # | Entrez: 228005, 9360; Uniprot: A2AR02, Q13427 |
Catalog # | PA5-67601 |
Price | |
Order / More Info | PPIG Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |