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| Product Name | ERBB3, 20-643aa, Human, His tag, Baculovirus |
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| Description | MW: 95.6kDa (863aa) (100-150kDa in SDS-PAGE under reducing conditions.). Purity >90% by SDS-PAGE. ERBB3, also known as receptor tyrosine-protein kinase erbB-3, is a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. ErbB3 has been shown to bind the ligands heregulin and NRG-2. Ligand binding causes a change in conformation that allows for dimerization, phosphorylation, and activation of signal transduction. ErbB3 can heterodimerize with any of the oth |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [Receptor tyrosine-protein kinase erbB-3 isoform; c-erbB-3; ErbB-3; erbB3-S; HER3; LCCS2; MDA-BF-1; p180-ErbB3; p45-sErbB3; p85-sErbB3] |
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| Gene, Accession, CAS # | ERBB3, Gene ID: 2065, Accession: NP_001973 |
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| Catalog # | MBS206062 |
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| Order / More Info | ERBB3, 20-643aa, Human, His tag, Baculovirus from MYBIOSOURCE INC. |
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| Product Specific References | Wang S, et al (2010) Oncogene. 29 (29):4225-36. |
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