| 产品详情 |
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| Antigenic Specificity | RNF14 |
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| Clone | OTI1C9 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RNF14 Monoclonal Antibody (OTI1C9). The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported. |
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| Immunogen | n/a |
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| Other Names | ARA54, HFB30, TRIAD2, E3 ubiquitin-protein ligase RNF14, androgen receptor associated protein 54, androgen receptor-associated protein 54 |
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| Gene, Accession # | Entrez: 56736, 9604; Uniprot: Q9JI90, Q9UBS8 |
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| Catalog # | MA5-27387 |
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| Price | |
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| Order / More Info | RNF14 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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