| 产品详情 |
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| Antigenic Specificity | NSD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:25-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NSD1 Polyclonal Antibody. This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-bindin |
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| Immunogen | n/a |
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| Other Names | ARA267, KMT3B |
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| Gene, Accession # | Entrez: 64324; Uniprot: Q96L73 |
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| Catalog # | PA5-50857 |
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| Price | |
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| Order / More Info | NSD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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