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| Product Name | AKR1C1, 1-323aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 38.9 kDa (343aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. AKR1C1 is member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. R |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Aldo-keto reductase family 1 member C1; 20-alpha-HSD; DD1/DD2; HBAB; DDH; DDH1; Aldo-keto reductase family 1; member C1 20 alpha (3 alpha) hydroxysteroid dehydrogenase; 20 alpha hydroxysteroid dehydrogenase; 2ALPHAHSD; AK1C1; MBAB; Aldo keto reductase family 1 member C1; C9; Chlordecone reductase homolog; Chlordecone reductase homolog HAKRC; DD1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; H37; HAKRC; Hepatic dihydrodiol dehydrogenase; High affinity hepatic bile acid-binding pro |
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| Gene, Accession, CAS # | AKR1C1, Gene ID: 1645, Accession: NP_001344 |
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| Catalog # | MBS203641 |
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| Order / More Info | AKR1C1, 1-323aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Zhang Y., et al. (2000) J. Mol. Endocrinol. 25:221-228; Zhang Y., et al. (2009) Mol Cell Endicrinol. 298 (1-2):76-83; |
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