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| Product Name | AKR1C3, 1-323aa, Human, His tag, E Coli (Bioactivity Validated) |
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| Description | MW: 39 kDa (343 aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic disease |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Aldo-keto reductase family 1 member C3; Aldo-keto reductase family 1; member C3; DD3; DDX; HA1753; HAKRB; HAKRe; hluPGFS; HSD17B5; KIAA0119; Aldo-keto reductase family 1; member C3 17 beta HSD 5; AKR1 C3; Chlordecone reductase; 17 beta hydroxysteroid dehydrogenase type 5; Aldo keto reductase family 1 member C3; DDH1; HAKRe; HSD17B5; PGFS; Prostaglandin F synthase,] |
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| Gene, Accession, CAS # | AKR1C3, Gene ID: 8644, Accession: NP_003730 |
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| Catalog # | MBS203288 |
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| Order / More Info | AKR1C3, 1-323aa, Human, His tag, E Coli (Bioactivity Validated) from MYBIOSOURCE INC. |
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| Product Specific References | Davies N., et al. (2009) Cancer Res. 69 (11):4769-75; Kabututu Z., et al. (2009) J Biochem. 145 (2):161-8; |
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