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| Product Name | AKR1C3 Inhibitor I |
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| Description | MW: 317.36. Purity ≥98% by HPLC. Background: A highly potent and selective inhibitor of the type 5 17-beta-hydroxysteroid dehydrogenase AKR1C3. In repeat assays it showed an IC?? of 0.013 +/- 0.003 muM for AKR1C3, compared with 20.3 +/- 3.8 muM against AKR1C1 and >30 muM against AKR1C2 and AKR1C4. This inhibitor also showed displays potency in a cellular assay, blocking the ability of AKR1C3 to metabolize a proven substrate. Does not display any COX (cyclooxygenase) inhibition at 10 uM in who |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid] |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS841936 |
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| Order / More Info | AKR1C3 Inhibitor I from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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