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| Antigenic Specificity | Synuclein, alpha (SNCA) (pSer129) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson?s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Mutation of the alpha-synuclein gene is associated with familial forms of PD (Newmann et al., 2002). Recent evidence suggests that phosphorylation of alpha-synuclein at ser129 plays a role in the formation of inclusions in PD (Smith et al., 2005, Masliah et al., 2005). Anti-Phospho-Ser129 Alpha Synuclein Western blot of rat cortex lysate showing specific labeling of the ~15 k alpha synuclein protein phosphorylated at Ser129. Immunolabeling is blocked by the phosphopeptide (peptide) used as antigen but not by the corresponding dephosphopeptide (not shown). . |
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| Immunogen | n/a |
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| Other Names | snca|MGC64356|LOC619283|NACP|alphaSYN|PARK1|PARK4|PD1 |
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| Gene, Accession # | Gene ID: 29219 |
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| Catalog # | ABIN361526 |
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| Price | |
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| Order / More Info | Synuclein, alpha (SNCA) (pSer129) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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