| 产品详情 |
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| Antigenic Specificity | TRIM28 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRIM28 Polyclonal Antibody. TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation. |
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| Immunogen | n/a |
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| Other Names | TRIM28, Tripartite motif containing 28, KRAB-associated protein 1, KAP-1, KRAB-interacting protein 1, KRIP-1, RING finger protein 96, TIF1-beta |
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| Gene, Accession # | Entrez: 10155, 116698, 21849; Uniprot: O08629, Q13263, Q62318 |
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| Catalog # | PA5-34485 |
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| Price | |
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| Order / More Info | TRIM28 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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