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| Product Name | Mouse MDC (CCL22) Recombinant |
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| Description | MW: 10,302 Da. Purity >97%, as determined by SDS-PAGE and HPLC. CCL22 (monocyte-derived chemokine) was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells. One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatiti |
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| Size | 0.005 mg, 0.02 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mouse MDC Recombinant; ccl22; mdc; ccl-22; SCYA22] |
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| Gene, Accession, CAS # | CCL22, Gene ID: 20299, Accession: NP_033163.1 |
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| Catalog # | MBS553251 |
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| Order / More Info | Mouse MDC (CCL22) Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • lack of association with rheumatoid arthritis of selected polymorphisms in 4 candidate genes: cfh, cd209, Eotaxin-3, and mhc2ta .J Rheumatol, Aug 2009; 36: 1590 - 1595. • Eotaxin-3 is involved in churg-strauss syndrome - a serum marker closely correlating with disease activity .Rheumatology, Jun 2008; 47: 804 - 808. • dsrna enhances Eotaxin-3 production through interleukin-4 receptor upregulation in airway epithelial cells .Eur. Respir. J., Nov 2005; 26: 795 - 803. • chroni |
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