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| Product Name | Monkey sPECAM-1 ELISA (Monkey Platelet Endothelial Cell Adhesion Molecule ELISA) |
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| Description | PECAM-1 is a transmembrane glycoprotein with a molecular weight of approximately 130 kDa, depending on the degree of glycosylation. PECAM-1 is constitutively expressed on all vascular cells and has provided a useful immunohistochemical marker of blood vessels, particularly in the setting of angiogenesis. It has also been found on platelets, monocytes, neutrophils and CD8+ T cells. Bone marrow stem cells and transformed cell lines of the myeloid and megakaryocytic lineage also express PECAM-1. Interestingly, PECAM-1 was also detected on human, mouse and rat solid tumor lines. Recent studies suggest a role for PECAM-1 in the inflammatory process and leukocyte-endothelial interaction. PECAM-1 is an early and sensitive marker for tumor-induced angiogenesis. Several data have suggested that PECAM-1 may be involved in the process of angiogenesis in a developing vertebrate embryo as well as during metastases formation. Besides the membrane-bound form of PECAM-1 a soluble form of the molecule exists, which is 5-10 kDa smaller than cell-associated PECAM-1, and contains the cytoplasmic tail. Soluble PECAM-1 was detected in normal human plasma. Sample Types: cell culture, serum. Sample Size: 10 µL. Range: 0.48 - 30.0 U/mL. Sensitivity: 0.06 U/mL. Time: 3hr 10min |
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| Size | 96 wells |
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| Concentration | n/a |
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| Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 61-PECMK-E01 |
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| Order / More Info | Monkey sPECAM-1 ELISA (Monkey Platelet Endothelial Cell Adhesion Molecule ELISA) from ALPCO |
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| Product Specific References | n/a |
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