产品详情 |
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Antigenic Specificity | ALK |
Clone | SP8 |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:1-1:100, Immunofluorescence: 1:1-1:100, Immunohistochemistry (Paraffin): 1:50-1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ALK Monoclonal Antibody (SP8). Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in 30-50% of CD30+ large cell lymphomas (1). This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein (2). |
Immunogen | n/a |
Other Names | p80, ALK tyrosine kinase receptor, CD246 antigen, anaplastic lymphoma kinase, NBLST3, TFG/ALK |
Gene, Accession # | Entrez: 11682, 238; Uniprot: P97793, Q9UM73 |
Catalog # | MA5-14528 |
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Order / More Info | ALK Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 17660712, 19690765, 20223922, 22203052 |
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