| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD45RB |
|---|
| Clone | MB4B4 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, κ |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PE anti-mouse CD45RB. CD45RB is a 220 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. |
|---|
| Immunogen | anti-Ig activated murine B cells |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 19264 |
|---|
| Catalog # | 151603 |
|---|
| Price | |
|---|
| Order / More Info | CD45RB Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|