| 产品详情 |
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| Antigenic Specificity | CD45RB |
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| Clone | MB4B4 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | PerCP-Cyanine5.5 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PerCP/Cyanine5.5 anti-mouse CD45RB. CD45RB is a 220 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. |
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| Immunogen | anti-Ig activated murine B cells |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 19264 |
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| Catalog # | 151605 |
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| Price | |
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| Order / More Info | CD45RB Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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