| 产品详情 |
| Edit |   |
| Antigenic Specificity | CCR3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 50 ug |
| Concentration | n/a |
| Applications | Immunohistochemistry (Paraffin): 8 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CCR3 Polyclonal Antibody. CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. |
| Immunogen | n/a |
| Other Names | CC-CKR-3, CKR3, CMKBR3, MGC102841 |
| Gene, Accession # | Entrez: 1232; Uniprot: P51677 |
| Catalog # | PA5-33395 |
| Price | |
| Order / More Info | CCR3 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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