| 产品详情 |
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| Antigenic Specificity | CCR4 |
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| Clone | 4A3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR4 Monoclonal Antibody (4A3). CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of |
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| Immunogen | n/a |
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| Other Names | CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, C-C CKR-4, C-C chemokine receptor type 4, CCR-4, chemokine (C-C) receptor 4 |
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| Gene, Accession # | Entrez: 1233; Uniprot: P51679 |
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| Catalog # | MA5-24390 |
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| Price | |
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| Order / More Info | CCR4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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