| 产品详情 |
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| Antigenic Specificity | Tumor Protein P63 (TP63) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis . In addition to p53, mammalian cells contain two p53 family members, p63 and p73, which are similar to p53 in both structure and function . While p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Amplification of the p63 gene is frequently observed in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription intiation site that yields a 40 kDa deltaNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the alpha, beta and gamma isoforms . Synonyms: AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L, |
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| Immunogen | Recombinant protein of human TP63 |
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| Other Names | TP63|tp63|TP73L|AI528772|CCT|Cct1|Ccta|TRic|Tcp-1|Tp63|c-cpn|p63|AI462811|Ket|P51/P63|P63|P73l|Trp53rp1|AIS|B(p51A)|B(p51B)|EEC3|KET|LMS|NBP|OFC8|RHS|SHFM4|TP53CP|TP53L|p40|p51|p53CP|p73H|p73L|Tp73l|Trp63|DNp63|id:ibd3516|tp73l|wu:fc89f04|wu:fk85h07|wu:fk88b02|Xp63|ket|np63|tp73l-A|trp63|TRP63 |
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| Gene, Accession # | Gene ID: 8626,22061,246334 |
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| Catalog # | ABIN1684067 |
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| Price | |
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| Order / More Info | Tumor Protein P63 (TP63) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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