产品详情 |
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Antigenic Specificity | BRCA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRCA1 Polyclonal Antibody. • Target Background: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and |
Immunogen | KLH conjugated synthetic peptide derived from mouse BRCA1. Immunogen Range: 80-130/1812 |
Other Names | Breast cancer type 1 susceptibility protein homolog; Brca1 |
Gene, Accession # | Gene ID: 12189, SwissProt: P48754 |
Catalog # | bs-0803R |
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Order / More Info | BRCA1 Antibody from BIOSS ANTIBODIES |
Product Specific References | Wang, Da-Ting, et al. (2015) PeerJ. PubMed: 25780774 |
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