| Edit |   |
|---|
| Antigenic Specificity | BRCA2 |
|---|
| Clone | 3G7 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | Protein A purified |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | IF(ICC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | BRCA2 (3G7) Monoclonal Antibody. • Target Background: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May |
|---|
| Immunogen | Recombinant human BRCA2 protein, around N-terminal 200aa. |
|---|
| Other Names | FAD; FACD; FAD1; GLM3; BRCC2; FANCD; PNCA2; FANCD1; BROVCA2; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein; BRCA2 |
|---|
| Gene, Accession # | Gene ID: 675, SwissProt: P51587 |
|---|
| Catalog # | bsm-52025M |
|---|
| Price | |
|---|
| Order / More Info | BRCA2 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|