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Antigenic Specificity | BRCA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 647 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRCA2 Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May |
Immunogen | KLH conjugated synthetic peptide derived from human BRCA2. Immunogen Range: 1-50/3418 |
Other Names | FAD; FACD; FAD1; GLM3; BRCC2; FANCD; PNCA2; FANCD1; BROVCA2; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein; BRCA2 |
Gene, Accession # | Gene ID: 675, SwissProt: P51587 |
Catalog # | bs-1210R-A647 |
Price | |
Order / More Info | BRCA2 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |