| 产品详情 |
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| Antigenic Specificity | TCF3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCF3 Polyclonal Antibody. The TCF3 gene, also called E2A, encodes two basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. These transcription factors are involved in mediating canonical Wnt signaling, which is very important in a diverse array of cellular functions such as stem cell proliferation, self-renewal, activation, fate determination, differentiation and aging and senescence. They bind beta-catenin and can act as transcriptional activators or repressors for Wnt target genes, and have been shown to regulate specific target genes during CNS development downstream of Wnt signaling. TCF3/Lef complexes are also known to play key roles in controlling cell fate lineages in multipotent skin stem c |
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| Immunogen | n/a |
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| Other Names | E2A, E47, ITF1, TCF-3, VDIR, bHLHb21; VDR interacting repressor; class B basic helix-loop-helix protein 21; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; kappa-E2-binding factor; negative vitamin D response element-binding protein; transcription factor E2-alpha; transcription factor ITF-1; vitamin D receptor-interacting repressor |
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| Gene, Accession # | Entrez: 171046, 21423, 6929; Uniprot: P15806, P15923, P21677 |
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| Catalog # | PA5-20900 |
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| Price | |
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| Order / More Info | TCF3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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