| 产品详情 |
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| Antigenic Specificity | EGFR |
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| Clone | monoclonal |
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| Host Species | n/a |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) drug conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-EGFR-SMCC-DM1 ADC. This Antibody-Drug Conjugate (ADC) product is comprised of an anti-EGFRvIII monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 1956, UniProt: P00533 |
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| Catalog # | ADC-W-496 |
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| Price | |
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| Order / More Info | EGFR Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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| 产品资料 |
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