| 产品详情 |
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| Antigenic Specificity | Thymidine Phosphorylase |
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| Clone | P-GF.44C |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C). Platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites. |
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| Immunogen | n/a |
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| Other Names | gliostatin, tdRPase |
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| Gene, Accession # | Entrez: 1890, 315219, 72962; Uniprot: P19971, Q5FVR2, Q99N42 |
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| Catalog # | MA5-13542 |
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| Price | |
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| Order / More Info | Thymidine Phosphorylase Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10537355, 14601101, 16132760, 16282698, 17006982, 17378915, 17762932, 18207190, 18381946, 19127259, 19457654, 19513500, 19654105, 20214978, 20696678, 20700125, 21170649, 21187521, 21896999, 25793299 |
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