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| Product Name | Human IL-33 Recombinant Protein |
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| Description | Human IL-33 Recombinant Protein. IL-33 (Interleukin-33) is a 270 amino acid, highly divergent protein belonging to the IL-1 family with an IL-1-like C-terminal domain. IL-33 is a dual function protein that may function both as a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. IL-33 binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6. IL-33 activates NF-kappaB and MAP kinases, and drives production of TH2-associated cytokines from in vitro polarized TH2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. IL-33 is proteolytically converted to a mature form by CAS |
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| Size | 10 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay Dependent |
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| Other Names | H-IL-33 |
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| Gene, Accession, CAS # | Entrez: 90865; Uniprot: O95760 |
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| Catalog # | RP-8623 |
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| Order / More Info | Human IL-33 Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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