| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD8a |
|---|
| Clone | 53-6.7 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2a, κ |
|---|
| Format | purified, azide-free |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC), CyTOF®, IHC, IP, Depletion, Block |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | LEAF™ Purified anti-mouse CD8a. CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
|---|
| Immunogen | Mouse thymus or spleen |
|---|
| Other Names | T8, Lyt2, Ly-2 |
|---|
| Gene, Accession # | Gene ID: 12525 |
|---|
| Catalog # | 100735 |
|---|
| Price | |
|---|
| Order / More Info | CD8a Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|