| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Human APP (N-terminal, aa 1-14) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | unconjugated |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, IHC, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit Anti-Human APP (N-terminal) polyclonal antibody for ELISA, IHC, WB. Amyloid β (Aβ) is the peptide that accumulates in the brain in Alzheimer`s disease and certain classes of cerebrovascular angiopathy. Alzheimer`s disease (AD) is characterized by the progressive formation in the brain of insoluble amyloid plaques and vascular deposits consisting of the 4-kD Aβ-peptide. Aβ generation is initiated by proteolytic cleavage of the amyloid precursor protein (APP) at the N-terminal of Aβ by β-secretase. The Aβ peptide is then released by proteolytic cleavage at its C-terminus by g-secretase. The insoluble Aβ peptide forms aggregates in the vessels and senile plaques of AD brains. |
|---|
| Immunogen | Peptide (DAEFRHDSGYEVHH) |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 351, UniProt: P05067 |
|---|
| Catalog # | CABT-L521 |
|---|
| Price | |
|---|
| Order / More Info | Human APP (N-terminal, aa 1-14) Antibody from CREATIVE DIAGNOSTICS |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|