| 产品详情 |
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| Product Name | Picropodophyllotoxin |
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| Description | Orally active insulin-like growth factor 1 receptor (IGF1R) inhibitor that exhibits no activity at the insulin receptor, FGFR, PDGFR or EGFR. Inhibits IGF1R autophosphorylation (IC50 ~ 1 nM), increases the fraction of cells in the G2/M phase and upregulates apoptosis. Exhibits antiproliferative effects in multiple cancer cell lines (IC50 = 0.05 - 15 μM), and has anticancer and antineovascularization activity in vivo. Purity 97%. MW (observed): 414.41 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. Picropodophyllin |
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| Gene, Accession, CAS # | CAS: 477-47-4 |
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| Catalog # | 2956/10 |
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| Price | |
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| Order / More Info | Picropodophyllotoxin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26503322, 28793874 |
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| 产品资料 |
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