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| Antigenic Specificity | Notch, extracellular domain, EGF repeats #12-20 |
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| Clone | C458.2H |
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| Host Species | Mouse |
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| Reactive Species | Drosophila |
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| Isotype | IgG1, kappa light chain |
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| Format | supernatant |
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| Size | 1.0 ml |
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| Concentration | n/a |
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| Applications | Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epitope: extracellular domain, EGF repeats #12-20 [see depositor notes]. This antibody was generated against the extracellular domain of Notch containing the EGF repeats #12-20. The Neurogenic locus Notch protein functions as a transmembrane receptor for membrane-bound ligands Delta and Serrate to regulate neurodevelopment. Upon ligand activation, the intracellular domain (NICD) is released from the cell membrane, and forms a transcriptional activator complex with the Suppressor of hairless protein. |
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| Immunogen | Recombinant fusion protein containing the EGF repeats #12-20: Partial protein |
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| Other Names | CG3936, Notch, NECD, NICD |
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| Gene, Accession # | N, Gene ID: 31293, UniProt: P07207 |
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| Catalog # | C458.2H |
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| Price | |
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| Order / More Info | Notch, extracellular domain, EGF repeats #12-20 Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
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| Product Specific References | PubMed: 8162848, 10704384, 10519550, 8162848, 11533661, 12526814, 10206647, 23318643, 18194540, 10704384, 15809035, 20063416, 21965616, 10491396, 17287246, 18948267, 20063416, 18948267 |
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