| 产品详情 |
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| Product Name | Recombinant Human Dehydrogenase/reductase SDR family member 2 (DHRS2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 58.5kDa. Full Length of Isoform 2: 1-300aa. N-terminal GST-tagged. Homo sapiens (Human). Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Dicarbonyl reductase HEP27; Protein D; Short chain dehydrogenase/reductase family 25C member 1 |
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| Gene, Accession, CAS # | DHRS2, UniProt: Q13268 |
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| Catalog # | RPC22990 |
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| Order / More Info | Recombinant Human Dehydrogenase/reductase SDR family member 2 (DHRS2) from BIOMATIK |
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| Product Specific References | n/a |
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