| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | LSD1 |
|---|
| Clone | 1B2E5 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, nonhuman primate |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | LSD1 Monoclonal Antibody (1B2E5). LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the |
|---|
| Immunogen | n/a |
|---|
| Other Names | KDM1; LSD1; BHC110; KIAA0601; RP1-184J9.1; AOF2 |
|---|
| Gene, Accession # | Entrez: 23028, 99982; Uniprot: O60341, Q6ZQ88 |
|---|
| Catalog # | MA5-15273 |
|---|
| Price | |
|---|
| Order / More Info | LSD1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|