| 产品详情 |
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| Antigenic Specificity | Cyclin D3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin D3 Polyclonal Antibody. Cyclin D3 is a regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of |
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| Immunogen | n/a |
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| Other Names | CCND3, G1/S-specific cyclin-D3, G1/S-specific cyclin D3, D3-type cyclin, cyclin D3 |
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| Gene, Accession # | Entrez: 12445, 25193, 896; Uniprot: P30281, P30282, P48961 |
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| Catalog # | PA5-77891 |
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| Price | |
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| Order / More Info | Cyclin D3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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