| 产品详情 |
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| Antigenic Specificity | Cyclin E |
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| Clone | HE12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: Assay Dependent, Immunoprecipitation: 1 µg, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin E Monoclonal Antibody (HE12). Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
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| Immunogen | n/a |
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| Other Names | CCNE, CCNE1, G1/S-specific cyclin E1 |
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| Gene, Accession # | Entrez: 898; Uniprot: P24864 |
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| Catalog # | 32-1600 |
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| Price | |
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| Order / More Info | Cyclin E Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12188931, 17158783, 17192871, 19147773, 19585502, 21182779, 21298020, 21533191, 21616935, 26623720 |
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