| 产品详情 |
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| Antigenic Specificity | CD263 (TRAIL-R3) |
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| Clone | TRAIL-R3-02 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02). TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5). |
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| Immunogen | n/a |
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| Other Names | CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID |
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| Gene, Accession # | Entrez: 8794; Uniprot: O14798 |
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| Catalog # | MA1-19729 |
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| Price | |
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| Order / More Info | CD263 (TRAIL-R3) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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